Publications

Tang ZZ, Bunn P, Tao R, Liu Z, Lin DY (2017). PreMeta: a tool to facilitate meta-analysis of rare-variant associations. BMC Genomics. accepted.

Tang ZZ, Chen G, Alekseyenko AV, Li H (2016). A general framework for association analysis of microbial communities on a taxonomic tree. Bioinformatics. btw804.

Tang ZZ, Chen G, Alekseyenko AV (2016). PERMANOVA-S: Association test for microbial community composition that accommodates confounders and multiple distances, Bioinformatics, btw311.

Tang ZZ, Lin DY (2015). Meta-analysis for discovering rare-variant associations: statistical methods and software programs, American Journal of Human Genetics, 97, 35-53.

Stitziel NO, Won HH, Morrison AC, Peloso GM, Do R, ..., Tang ZZ, ..., Kathiresan S (2014)
Inactivating mutations in NPC1L1 and protection from coronary heart disease. New England Journal of Medicine, 371(22):2072-2082.

Tang ZZ, Lin DY (2014). Meta-analysis of sequencing studies with heterogeneous genetic associations, Genetic Epidemiology, 38(5):389-401.


Crosby J, Peloso GM, Auer PL, Crosslin D, Stitziel NO, Lange LA, Lu K, Tang ZZ, ..., Reiner AP, Boerwinkle E, Kathiresan S (2014). Rare loss-of-function mutations in the APOC3 gene, plasma triglycerides, and risk for coronary heart disease, New England Journal of Medicine, 235(2):e30-e31.


Lange LA, Hu Y, Zhang H, Xue C, Schmidt EM, Tang ZZ, ..., Willer CJ (2014). Novel rare and low frequency coding variants associated with LDL cholesterol, American Journal of Human Genetics, 94, 233-245.


Tang ZZ, Lin DY (2013). MASS: meta-analysis of score statistics for sequencing studies, Bioinformatics, 29, 1803-1805.


Lin DY, Zeng D, Tang ZZ (2013). Quantitative trait analysis in sequencing studies under trait-dependent sampling, Proceedings of the National Academy of Sciences of the United States of America, 110, 12247–12252

Nelson MR, Wegmann D, Ehm MG, Kessner D, Jean PS, Verzilli C, Shen J, Tang Z, ..., Novembre J, Mooser V (2012). An abundance of rare functional variants in 202 drug target genes sequenced in 14,002 people, Science, 337, 100-104.


Yang EY, Chambless L, Sharrett AR, Virani SS, Liu X, Tang Z, Boerwinkle E, Ballantyne CM, Nambi V (2012). Carotid arterial wall characteristics are associated with incident ischemic stroke but not coronary heart disease in the Atherosclerosis Risk in Communities (ARIC) study, Stroke, 43, 103-108.


Lin DY, Tang ZZ (2011). A general framework for detecting disease associations with rare variants in sequencing studies, American Journal of Human Genetics, 89, 354-367.


Yang EY, Nambi V, Tang Z, Virani SS, Boerwinkle E, Hoogeveen RC, Astor BC, Mosley TH, Coresh J, Chambless L, Ballantyne CM (2009). Clinical implications of JUPITER (Justification for the Use of statins in Prevention: an Intervention Trial Evaluating Rosuvastatin) in a U.S. population insights from the ARIC (Atherosclerosis Risk in Communities) study, Journal of the American College of Cardiology, 54, 2388-2395.


Sun W, Wright FA, Tang Z, Nordgard SH, Van Loo P, Yu T, Kristensen VN, Perou CM (2009). Integrated study of copy number states and genotype calls using high-density SNP arrays, Nucleic Acids Research, 37, 5365-5377